Protein folding stability measured at scale

Protein folding stability measured at scale

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https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs00249-019-01362-7/MediaObjects/249_2019_1362_Fig1_HTML.png

Thermodynamics of protein folding: methodology, data analysis and interpretation of data

https://www.pnas.org/cms/10.1073/pnas.1411798111/asset/8fe64cca-d41b-47c0-a1de-fc2fc0360c0a/assets/graphic/pnas.1411798111fig03.jpeg

The nature of protein folding pathways

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Publications The Fitzgerald Lab

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Thermodynamics of protein folding: methodology, data analysis and interpretation of data

https://www.pnas.org/cms/10.1073/pnas.1610272113/asset/5d359f9d-e544-4e03-8a0a-ce0b57bb3d18/assets/graphic/pnas.1610272113fig01.jpeg

Quantitative determination of ribosome nascent chain stability

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Computational Modeling of Protein Stability: Quantitative Analysis Reveals Solutions to Pervasive Problems - ScienceDirect

https://ars.els-cdn.com/content/image/1-s2.0-S2405471221001952-gr1.jpg

Fundamentals to function: Quantitative and scalable approaches for measuring protein stability - ScienceDirect

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The Stability of a Three-State Unfolding Protein

https://www.pnas.org/cms/10.1073/pnas.2122676119/asset/80791442-6436-4daa-a596-b03c6a0ddf24/assets/images/large/pnas.2122676119fig04.jpg

Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation

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A one-pot analysis approach to simplify measurements of protein stability and folding kinetics - ScienceDirect

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Mega-scale experimental analysis of protein folding stability in biology and design

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Robust membrane protein tweezers reveal the folding speed limit of helical membrane proteins